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Patrick Dempsey Describes His Audition For \'Grey\'s Anatomy\' & His First Read with Ellen Pompeo!

Patrick Dempsey looks suave and as handsome as ever on the cover of

Here’s what the 48-year-old actor had to share with the mag:

: “At first I thought [Shonda] hated me, but she was calculating in her head where to put me and what I’d be right for…they liked me, but they wanted me to do a chemistry read with [lead actress Ellen Pompeo]. I had an immediate connection with her because she has a Boston accent, and I’m from Maine, so that disarmed me.”

On the Patrick Dempsey Center for Cancer Hope & Healing: “My experience…is that the doctors have such a huge workload; they’re trying to do everything that they can; the nurses are so vitally important as well—but then what happens to the caregivers and the family members? There is a real void, and that’s how the center came about, [with the] thinking: How do we help those people? The human touch is so healing, and when people come into the center, they’re greeted usually by cancer survivors themselves who already know what’s going on and are compassionate. I think that’s really important, and sometimes you don’t get that.”

On his wife Jillian‘s opinion of his racing: “I think she kind of wishes she hadn’t allowed me to start racing because it’s become a full-time business and occupation outside of, and on top of, everything else I’m doing. She got the new Porsche 911 Targa as an anniversary present and now says, ‘I completely understand why you love cars and the rush of it!’ If you’re in a performance car there’s definitely a sensation that you get that is indescribable.”

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