Spoiler Chat: Noooooo! Heartbreak Comes to Grey's Anatomy 

i think the hook up might be Jackson and Lexie

I hope the picture of Derek and Meredith is supposed to mislead us.

Honestly if it is Cristina/Owen i'll stop watching the show, because they are the only reason why i bother to watch the show anymore.

So i'm hoping it's Callie/Arizona (even though i kinda like them) because of the baby issue

I hope it is Cristina/Owen!
Not because I don't like them but because I like Callie/Arizona more and if it is Derek/Meredith i'll stop watching the show!!!
Like smileyface197 I think the hook up will be Lexie and Jackson.

hook up is Lexie and Jackosn the breakup is Callie and Arizona their is no way its merder they have no issues