The Archangel Michael (Paul Bettany) falls to Earth in Los Angeles. He cuts off his wings and steals a police car after a policeman is killed por another officer who is possessed. He then heads for the Paradise Falls diner, near the edge of the Mojave Desert.

Meanwhile, Kyle (Tyrese Gibson), a single father driving to L.A., stops at the diner. There he meets the owner, Bob Hanson (Dennis Quaid); his son Jeep (Lucas Black); the short-order cook Percy (Charles S. Dutton); a pregnant waitress, Charlie (Adrianne Palicki); a married couple, Howard and Sandra Anderson (Jon Tenney and Kate Walsh), and...