A hot-shot race-car gets waylaid in Radiator Springs, where he finds the true meaning of friendship and family.
Successful rookie racer Lightning McQueen has, to his pleasure, just won a 3-way tie with elder rival Chick Hicks and champ "The King", but is also proud and unappreciative of long-time (mostly older) supporters enough to have his ignored pit-crew desert him. Accidentally lost en route to California for the tie-breaker, he crashes through Radiator Springs on Route 66, destroying the road and some property. Forced to remain in town until he repairs them, he\'s stuck in a small community whose tight-knit inhabitants accept neither his selfishness nor bad attitude. Refusing to respect them initially, he eventually returns the friendship of redneck Mater and falls in love with Sally, but can\'t seem to get gruff Doc Hudson, who keeps a painful secret, to change his mind about him. Soon Lightning learns the inhabitants of the town as a whole, who are almost a secret to the outside world, also had a past now painfully absent, and tries to help them enjoy it once more.
Owen Wilson as Lightning McQueen, described by John Lasseter in the LA Times as "A hybrid between a stock car and a more curvaceous Le Mans endurance racer."
Paul Newman as Doc Hudson, a 1951 Hudson Hornet who is later revealed to be the Fabulous Hudson Hornet.
Bonnie Hunt as Sally Carrera, a 2002 996-series Porsche 911 Carrera.
Larry the Cable Guy as Mater, a 1951 International Harvester L-170 "boom" truck with elements of a mid-1950s Chevrolet. One-Ton Wrecker Tow Truck.
Cheech Marin as Ramone, a 1959 Chevrolet Impala Lowrider.
Michael Wallis as Sheriff, a 1949 Mercury Club Coupe (police package).
Paul Dooley as Sarge, a 1941 Willys model jeep, in the style used by the US Military.
Jenifer Lewis as Flo, a 1957 Motorama show car.
Guido Quaroni as Guido, a custom forklift, resembling an Isetta at the front.
Richard Petty as Strip "The King" Weathers. The car\'s design was based on Richard Petty\'s 1970 Plymouth Superbird
Michael Keaton as Chick Hicks, described by Pixar as a generic 1980s stock car. Strongly resembles a 1978–88 General Motors G-Body such as a Buick Regal or Chevrolet Monte Carlo.
Katherine Helmond as Lizzie, a 1923 Ford Model T.
John Ratzenberger as Mack, a 1985 Mack Super-Liner.
Joe Ranft as Red, a 1960s style fire truck
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