Jared Leto, the colorful character actor -- and well-known frontman for the popular band 30 segundos to Mars -- will receive the Hollywood Breakout Performance Award for his work in Jean-Marc Vallee's Dallas Buyers Club at the 17th annual Hollywood Film Awards -- the first awards show of the 2013 season -- on Oct. 21 at the Beverly Hilton, The Hollywood Reporter has learned exclusively.

anterior recipients of the Hollywood Breakout Performance Award include Carey Mulligan, Michael Shannon, Joseph Gordon-Levitt and John Hawkes.

Leto, 41, has been atuação for years. He first rose to prominence on the TV show My So-Called Life (1994-1995), and then transitioned into films, including Steve James' Prefontaine (1997), Terrence Malick's The Thin Red Line (1998), James Mangold's Girl, Interrupted (1999), Darren Aronofsky's Requiem for a Dream (2000), Fincher's Panic Room (2002), Mary Harron's American Psycho (2000), Andrew Niccol's Lord of War (2005) and J.P. Schaefer's Chapter 27 (2007), a Mark David Chapman biopic for which he famously gained 67 pounds.

In Dallas Buyers Club, which premiered at the Toronto International Film Festival earlier this month, Leto is virtually unrecognizable as Rayon, a male-to-female transsexual -- inspired por a real person -- who is diagnosed with AIDS during the early days of the epidemic. Leto's character becomes an unlikely associate and business partner of Matthew McConaughey's Ron Woodroof, who begins importing and selling non-toxic, anti-viral medications that have not been approved por the FDA but have proven vastly mais effective than any that have been. They don't stop the progression of the deadly plague, but they slow it considerably. (Leto shed 40 pounds to play the part.)